Clues to why most survived China melamine scandal

WASHINGTON (AP) — Scientists wondering why some children and not others survived one of China's worst food safety scandals have uncovered a suspect: germs that live in the gut.

In 2008, at least six babies died and 300,000 became sick after being fed infant formula that had been deliberately and illegally tainted with the industrial chemical melamine. There were some lingering puzzles: How did it cause kidney failure, and why wasn't everyone equally at risk?

A team of researchers from the U.S. and China re-examined those questions in a series of studies in rats. In findings released Wednesday, they reported that certain intestinal bacteria play a crucial role in how the body handles melamine.

The intestines of all mammals teem with different species of bacteria that perform different jobs. To see if one of those activities involves processing melamine, researchers from the University of North Carolina at Greensboro and Shanghai Jiao Tong University gave lab rats antibiotics to kill off some of the germs — and then fed them melamine.

The antibiotic-treated rats excreted twice as much of the melamine as rats that didn't get antibiotics, and they experienced fewer kidney stones and other damage.

A closer look identified why: A particular intestinal germ — named Klebsiella terrigena — was metabolizing melamine to create a more toxic byproduct, the team reported in the journal Science Translational Medicine.

Previous studies have estimated that fewer than 1 percent of healthy people harbor that bacteria species. A similar fraction of melamine-exposed children in China got sick, the researchers wrote. But proving that link would require studying stool samples preserved from affected children, they cautioned.

Still, the research is pretty strong, said microbiologist Jack Gilbert of the University of Chicago and Argonne National Laboratory, who wasn't involved in the new study.

More importantly, "this paper adds to a growing body of evidence which suggests that microbes in the body play a significant role in our response to toxicity and in our health in general," Gilbert said.

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Dorner manhunt leads to deadly standoff

Human remains have been discovered in the debris of a burned cabin in Big Bear. While authorities can't confirm the remains are those of Christopher Dorner, it appears likely they are.

When authorities hemmed in the man they suspected of killing three people in a campaign of revenge that has gripped Southern California, he responded as they had feared: with smoke bombs and a barrage of gunfire.

The suspect, who police believe is fugitive ex-cop Christopher Dorner, shot to death one San Bernardino County sheriff's deputy and injured another Tuesday. He then barricaded himself in a wood cabin outside Big Bear in the snow-blanketed San Bernardino Mountains, police said.

Just before 5 p.m., authorities smashed the cabin's windows, pumped in tear gas and called for the suspect to surrender. They got no response. Then, using a demolition vehicle, they tore down the cabin's walls one by one. When they reached the last wall, they heard a gunshot.

PHOTOS: Manhunt for ex-LAPD officer

Then the cabin burst into flames. By late Tuesday evening, the smoldering ruins remained too hot for police to enter, but authorities said they believed Dorner's body was inside.

The standoff appeared to end a weeklong hunt for the former L.A. police officer and Navy reserve lieutenant, who is also suspected of killing an Irvine couple and a Riverside police officer. But Los Angeles Police Chief Charlie Beck said he would not consider the manhunt over until a body was recovered and identified as Dorner.

"It is a bittersweet night," said Beck as he drove to the hospital where the injured deputy was undergoing surgery. "This could have ended much better, it could have ended worse. I feel for the family of the deputy who lost his life."

TIMELINE: Manhunt for ex-LAPD officer

According to a manifesto Dorner allegedly posted on Facebook, he felt the LAPD unjustly fired him in 2009, when a disciplinary panel determined that he lied in accusing his training officer of kicking a mentally ill man during an arrest. Beck has promised to review the case.

Dorner, 33, vowed to wage "unconventional and asymmetrical warfare" against law enforcement officers and their families, the manifesto said. "Self-preservation is no longer important to me. I do not fear death as I died long ago."

Last week, authorities had tracked Dorner to a wooded area near Big Bear Lake. They found his torched gray Nissan Titan with several weapons inside. The only trace of Dorner was a short trail of footprints in newly fallen snow.

FULL COVERAGE: Sweeping manhunt for ex-cop

On Tuesday morning two maids entered a cabin in the 1200 block of Club View Drive and ran into a man who they said resembled the fugitive, a law enforcement official said. The cabin was not far from where Dorner's singed truck had been found and where police had been holding press conferences about the manhunt.

The man tied up the maids, and he took off in a purple Nissan parked near the cabin. About 12:20 p.m., one of the maids broke free and called police.

Nearly half an hour later, officers with the California Department of Fish and Wildlife spotted the stolen vehicle and called for backup. The suspect turned down a side road in an attempt to elude the officers but crashed the vehicle, police said.

A short time later, authorities said the suspect carjacked a light-colored pickup truck. Allan Laframboise said the truck belonged to his friend Rick Heltebrake, who works at a nearby Boy Scout camp.

Heltebrake was driving on Glass Road with his Dalmatian, Suni, when a hulking African American man stepped into the road, Laframboise said. Heltebrake stopped. The man told him to get out of the truck.

"Can I take my dog?" Heltebrake asked, according to his friend.

"You can leave and you can take your dog," the man said. He then sped off in the Dodge extended-cab pickup — and quickly encountered two Department of Fish and Wildlife trucks.

As the suspect zoomed past the officers, he rolled down his window and fired about 15 to 20 rounds. One of the officers jumped out and shot a high-powered rifle at the fleeing pickup. The suspect abandoned the vehicle and took off on foot.

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After Retirement, Pope Will Live in Vatican City

ROME — Though it may have come as a shock Monday to the world’s one billion-plus Catholics, Pope Benedict XVI’s plan to retire on Feb. 28 appears to have been in the works for some time, and was known to a handful of close advisers.

Still unclear, however, are some of the practical consequences of Benedict’s decision, Vatican officials acknowledged Tuesday, from how the former pope will be addressed, to what to do with the papal ring used to seal important documents, traditionally destroyed upon a pope’s death.“There are a series of questions that remain to be seen, also on the part of the pope himself, even if it is a decision that he had made some time ago,” the Rev. Federico Lombardi, the Vatican spokesman, said at a news conference. “How he will live afterward, which will be very different from how he lives now, will require time and tranquillity and reflection and a moment of adaptation to a new situation.”

Even though the Code of Canon Law allows popes to resign, the occurrence was rare enough to have caught Vatican officials off guard, including on issues like the protocol and potentially awkward logistics of having a former pope and his successor share a backyard.

When he leaves the papacy at the end of the month, Benedict will retire to his summer home in Castel Gandolfo, in the hills outside Rome, before moving to the Mater Ecclesiae convent, a plain, four-story structure built 21 years ago to serve as an international place “for contemplative life within the walls of Vatican City,” as it is described on a Vatican Web site.

Workers began transforming the building into a residence in November, after the cloistered nuns who had occupied the convent left, Father Lombardi said. He did not tip his hand about whether the renovations were carried out with the pontiff as the future occupant in mind. “The pope knew this place, this building and thought it was appropriate for his needs,” he said.

The timing, however, raised suspicions that the pope had been planning the details of his retirement for some time. The editor of the Vatican newspaper, L’Osservatore Romano, wrote Monday that the pope had made his decision “many months ago,” after a demanding trip to Mexico and Cuba in March 2012, “and kept with a reserve that no one could violate.”

Father Lombardi said that the stress of that trip had further convinced the pope that he no longer had the stamina to do the job.

In fact, the pope had meditated on the possibility of resigning for years. In the 2010 book “Light of the World: The Pope, the Church and the Signs of the Times,” from a series of interviews conducted by Peter Seewald, a German journalist, Benedict said that if a pope “clearly realized that he is no longer physically, psychologically and spiritually capable of carrying out the duties of his office,” he would have “the right, and under some circumstances also an obligation, to resign.”

Rumors of his imminent resignation began to appear periodically in the Italian news media in recent years, as the pope appeared increasingly frail in public appearances.

A Vatican official, who asked not to be named because he was discussing papal business, said that the number of people who had known about the pope’s decision “a long time, could be counted on one hand.” But the pope had informed a small group of other collaborators “in recent days.”

When he retires to Vatican City, the pope will be able to move freely, Father Lombardi said, though it was “premature” to say how involved he will be in day-to-day activities — like saying Mass — at the Vatican.

He would not, however, intervene in the choice of his successor. “You can be sure that the cardinals will be autonomous in their decision and he will have no specific role in this election,” Father Lombardi said, adding that the pope was “a very discreet person.”

The conclave to choose the next pope will begin 15 to 20 days after the pope resigns, and a new leader of the Roman Catholic Church is expected to be in place by Easter, which falls on March 31 this year.

Father Lombardi said the pope would continue to perform his regular duties until the end of the month, and would keep all the appointments on his calendar. Some parts of his schedule will be modified to take into account the heightened public interest in the pope during his final days in office, Father Lombardi indicated.

For instance, this week’s commemoration of Ash Wednesday, beginning the 40-day period of Lent preceding Easter, usually takes place in a church on the Aventine Hill. But this year it will be conducted in St. Peter’s Basilica at the Vatican instead, to allow a greater number of the faithful to attend, Father Lombardi said.

His final audience, on Feb. 27, will be moved to St. Peter’s Square instead of the usual indoor venue used in winter, “to allow the faithful to say goodbye to the pope.”

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Lady Gaga: I Can't Walk Due to Injury

02/12/2013 at 06:45 PM EST

Lady Gaga is feeling like a little monster for postponing concerts because of an injury.

"I barely know what to say," she writes on her Facebook page, Tuesday. "I've been hiding a show injury and chronic pain for some time now, [and] over the past month it has worsened. I've been praying it would heal. I hid it from my staff. I didn't want to disappoint my amazing fans. However, after last night's performance I could not walk and still can't."

The pop star, 26 – whose Twitter page explains that she has a case of synovitis, which is severe inflammation of the joints – was forced to postpone two concerts in Chicago, one in Detroit and one in Hamilton, Ontario.

"I hope you can forgive me, as it is nearly impossible for me to forgive myself," the rest of her Facebook post says. "I'm devastated & sad. It will hopefully heal as soon as possible. I hate this. I hate this so much. I love you and I'm sorry."

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Ex-Bell officials defend themselves as honorable public servants

Less than three years ago, they were handcuffed and taken away in a case alleged to be so extensive that the district attorney called it "corruption on steroids."

But on Monday, two of the six former Bell council members accused of misappropriating money from the small, mostly immigrant town took to the witness stand and defended themselves as honorable public servants who earned their near-$100,000 salaries by working long hours behind the scenes.

During her three days on the stand, Teresa Jacobo said she responded to constituents who called her cell and home phone at all hours. She put in time at the city's food bank, organized breast cancer awareness marches, sometimes paid for hotel rooms for the homeless and was a staunch advocate for education.

"I was working very hard to improve the lives of the citizens of Bell," she said. "I was bringing in programs and working with them to build leadership and good families, strong families."

Jacobo, 60, said she didn't question the appropriateness of her salary, which made her one of the highest-paid part-time council members in the state.

Former Councilman George Mirabal said he too worked a long, irregular schedule when it came to city affairs.

"I keep hearing time frames over and over again, but there's no clock when you're working on the council," he said Monday. "You're working on the circumstances that are facing you. If a family calls … you don't say, '4 o'clock, work's over.' "

Mirabal, 65, said he often reached out to low-income residents who didn't make it to council meetings, attended workshops to learn how to improve civic affairs and once even made a trip to a San Diego high school to research opening a similar tech charter school in Bell.

"Do you believe you gave everything you could to the citizens of Bell?" asked his attorney, Alex Kessel.

"I'd give more," Mirabal replied.

Both Mirabal and Jacobo testified that not only did they perceive their salaries to be reasonable, but they believed them to be lawful because they were drawn up by the city manager and voted on in open session with the city attorney present.

Mirabal, who once served as Bell's city clerk, even went so far as to say that he was still a firm supporter of the city charter that passed in 2005, viewing it as Bell's "constitution." In a taped interview with authorities, one of Mirabal's council colleagues — Victor Bello — said the city manager told him the charter cleared the way for higher council salaries.

Prosecutors have depicted the defendants as salary gluttons who put their city on a path toward bankruptcy. Mirabal and Jacobo, along with Bello, Luis Artiga, George Cole and Oscar Hernandez, are accused of drawing those paychecks from boards that seldom met and did little work. All face potential prison terms if convicted.

Prosecutors have cited the city's Solid Waste and Recycling Authority as a phantom committee, created only as a device for increasing the council's pay. But defense attorneys said the authority had a very real function, even in a city that contracted with an outside trash company.

Jacobo testified that she understood the introduction of that authority to be merely a legal process and that its purpose was to discuss how Bell might start its own city-run trash service.

A former contract manager for Consolidated Disposal Service testified that Bell officials had been unhappy with the response time to bulky item pickups, terminating their contract about 2005, but that it took about six years to finalize because of an agreement that automatically renewed every year.

Deputy Dist. Atty. Edward Miller questioned Mirabal about the day shortly after his 2010 arrest that he voluntarily told prosecutors that no work was done on authorities outside of meetings.

Mirabal said that if he had made such a statement, it was incorrect. He said he couldn't remember what was said back then and "might have heed and hawed."

"So it's easy to remember now?" Miller asked.

"Yes, actually."

"More than two years after charges have been filed, it's easier for you to remember now that you did work outside of the meetings for the Public Finance Authority?"

"Yes, sir."

Miller later asked Mirabal to explain a paragraph included on City Council agendas that began with the phrase, "City Council members are like you."

After some clarification of the question, Mirabal answered: "That everybody is equal and that if they look into themselves, they would see us."

corina.knoll@latimes.com

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Syrian Insurgents Claim to Control Large Hydropower Dam

BEIRUT, Lebanon — Syrian insurgents and opposition activists said Monday that rebel forces had taken control of Syria’s largest hydroelectric dam, an assertion that, if confirmed, would give them significant control over a vital reservoir and what remains of the sporadic power supplies in their war-ravaged country.

The Tabqa Dam, built more than 40 years ago with Russian help on the Euphrates River in northeast Syria’s Raqqa Province, provides electricity to areas that are both in rebel and loyalist hands, including the contested city of Aleppo, and would be the third Euphrates dam taken by the rebels, who control two smaller facilities upriver.

But the Tabqa Dam, which the government once boasted had made Syria self-sufficient in power generation, is considered a more potent weapon in the battle for allegiances in the nearly two-year-old Syria conflict. Rebel-held areas have been systematically denied electricity by President Bashar al-Assad’s forces in their effort to turn the population against the insurgency.

Claims that the Tabqa Dam was now in rebel control came as a possible new confrontation was brewing between Turkey and Syria after a Syrian minivan exploded just inside Turkish territory at Cilvegozu, an important border crossing near the rebel-held Syrian town of Bab al-Hawa. The blast killed at least 13 people, including 3 Turkish civilians; wounded at least 28; and damaged at least 19 vehicles.

The Turkish fatalities were believed to be the first related to the Syrian conflict since October, when a Syrian mortar shell killed five Turks near the border-crossing town of Akcakale, Turkey, eliciting a warning of retaliation by the Turkish government.

Turkey’s deputy prime minister, Bulent Arinc, did not rule out a bombing or suicide attack as the cause of the Cilvegozu explosion, and said all possibilities were under investigation at the border post in southern Turkey’s Hatay Province. But Syrian rebels, who get military and financial support from Turkey, quickly blamed Mr. Assad’s government for the explosion. Turkey, which hosts nearly 200,000 Syrian refugees, has repeatedly warned Mr. Assad’s government that it would not tolerate attacks along the 550-mile border.

Reports by rebel commanders and by the Syrian Observatory for Human Rights, an opposition group based in Britain with a network of contacts in Syria, said insurgents had met little resistance as they swept into the Tabqa area on Sunday, seizing the dam and setting fire to an imposing statue of President Assad’s father and predecessor, Hafez, in the city of Tabqa.

The reservoir created by the dam, known as Lake Assad, is Syria’s largest and is vital for irrigating area farms and supplying drinking water to Aleppo.

The Syrian government did not confirm the insurgent claims. But videos uploaded on the Internet by insurgents appeared to corroborate they were in control of areas inside and outside the dam, although not necessarily the control room. One rebel fighter was quoted as saying the insurgents intended to divert power from the dam to rebel-held areas.

“We will cut all sources for the regime,” said the fighter, who identified himself by a first name, Nawaf.

He said that rebels also had taken control of large areas of Tabqa, including a military police barracks, an air force facility and an artillery base, seizing weapons and ammunition, and that they did not intend to damage any infrastructure.

“The Shabiha says, ‘Assad or burn the country,’ ” he said, using the term for the feared plainclothes pro-government militias. “We say, ‘We will burn Assad and keep the country.’ ”

The Syrian Observatory for Human Rights, which had a similar account of events, also said rebel fighters had seized control of three neighborhoods that housed dam workers.

“The regime forces showed no resistance, while heads of security branches escaped using helicopters through Al Tabqa military airport,” the Observatory said in a statement. “The small town embodies the diverse Syrian society, as it has residents from different sects and ethnicities. The fighters have pledges not to harm any of the citizens.”

Fighters in the operation included members of the al-Nusra Front, the Islamic militant group that has developed a reputation for its fearless attacks on Mr. Assad’s military but has emerged as a problem for the United States. The United States wants to aid the insurgency but considers Al Nusra a terrorist organization with ties to Al Qaeda in Iraq.

Hwaida Saad reported from Beirut, and Rick Gladstone from New York. Reporting was contributed by Anne Barnard in Beirut; Sebnem Arsu and David D. Kirkpatrick in Gaziantep, Turkey; and an employee of The New York Times in Damascus, Syria.

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It's a Girl for John Cho

Mom & Babies
Celebrity Baby Blog

02/11/2013 at 06:30 PM ET

Paul Drinkwater/NBC

Surprise: Actor John Cho is a dad again!

The Go On star and his wife welcomed a daughter recently, Cho’s rep confirms to PEOPLE exclusively.

Baby girl is the second child for the couple, who are also parents to a son. No further details are available.

Cho currently stars alongside Jason Bateman in Identity Thief and will reprise his role as Hikaru Sulu in Star Trek Into Darkness in May.

He is also well known for his roles in American Pie and the Harold and Kumar films.

– Anya Leon with reporting by Julie Jordan

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Pope shows lifetime jobs aren't always for life

The world seems surprised that an 85-year-old globe-trotting pope who just started tweeting wants to resign, but should it be? Maybe what should be surprising is that more leaders his age do not, considering the toll aging takes on bodies and minds amid a culture of constant communication and change.

There may be more behind the story of why Pope Benedict XVI decided to leave a job normally held for life. But the pontiff made it about age. He said the job called for "both strength of mind and body" and said his was deteriorating. He spoke of "today's world, subject to so many rapid changes," implying a difficulty keeping up despite his recent debut on Twitter.

"This seemed to me a very brave, courageous decision," especially because older people often don't recognize their own decline, said Dr. Seth Landefeld, an expert on aging and chairman of medicine at the University of Alabama at Birmingham.

Age has driven many leaders from jobs that used to be for life — Supreme Court justices, monarchs and other heads of state. As lifetimes expand, the woes of old age are catching up with more in seats of power. Some are choosing to step down rather than suffer long declines and disabilities as the pope's last predecessor did.

Since 1955, only one U.S. Supreme Court justice — Chief Justice William Rehnquist — has died in office. Twenty-one others chose to retire, the most recent being John Paul Stevens, who stepped down in 2010 at age 90.

When Thurgood Marshall stepped down in 1991 at the age of 82, citing health reasons, the Supreme Court justice's answer was blunt: "What's wrong with me? I'm old. I'm getting old and falling apart."

One in 5 U.S. senators is 70 or older, and some have retired rather than seek new terms, such as Hawaii's Daniel Akaka, who left office in January at age 88.

The Netherlands' Queen Beatrix, who just turned 75, recently said she will pass the crown to a son and put the country "in the hands of a new generation."

In Germany, where the pope was born, Chancellor Angela Merkel, who is 58, said the pope's decision that he was no longer fit for the job "earns my very highest respect."

"In our time of ever-lengthening life, many people will be able to understand how the pope as well has to deal with the burdens of aging," she told reporters in Berlin.

Experts on aging agreed.

"People's mental capacities in their 80s and 90s aren't what they were in their 40s and 50s. Their short-term memory is often not as good, their ability to think quickly on their feet, to execute decisions is often not as good," Landefeld said. Change is tougher to handle with age, and leaders like popes and presidents face "extraordinary demands that would tax anybody's physical and mental stamina."

Dr. Barbara Messinger-Rapport, geriatrics chief at the Cleveland Clinic, noted that half of people 85 and older in developed countries have some dementia, usually Alzheimer's. Even without such a disease, "it takes longer to make decisions, it takes longer to learn new things," she said.

But that's far from universal, said Dr. Thomas Perls, an expert on aging at Boston University and director of the New England Centenarians Study.

"Usually a man who is entirely healthy in his early 80s has demonstrated his survival prowess" and can live much longer, he said. People of privilege have better odds because they have access to good food and health care, and tend to lead clean lives.

"Even in the 1500s and 1600s there were popes in their 80s. It's remarkable. That would be today's centenarians," Perls said.

Arizona Sen. John McCain turned 71 while running for president in 2007. Had he won, he would have been the oldest person elected to a first term as president. Ronald Reagan was days away from turning 70 when he started his first term as president in 1981; he won re-election in 1984. Vice President Joe Biden just turned 70.

In the U.S. Senate, where seniority is rewarded and revered, South Carolina's Strom Thurmond didn't retire until age 100 in 2002. Sen. Robert Byrd of West Virginia was the longest-serving senator when he died in office at 92 in 2010.

Now the oldest U.S. senator is 89-year-old Frank Lautenberg of New Jersey. The oldest congressman is Ralph Hall of Texas who turns 90 in May.

The legendary Alan Greenspan was about to turn 80 when he retired as chairman of the Federal Reserve in 2006; he still works as a consultant.

Elsewhere around the world, Cuba's Fidel Castro — one of the world's longest serving heads of state — stepped down in 2006 at age 79 due to an intestinal illness that nearly killed him, handing power to his younger brother Raul. But the island is an example of aged leaders pushing on well into their dotage. Raul Castro now is 81 and his two top lieutenants are also octogenarians. Later this month, he is expected to be named to a new, five-year term as president.

Other leaders who are still working:

—England's Queen Elizabeth, 86.

—Abdullah bin Abd al-Aziz al-Saud, king of Saudi Arabia, 88.

—Sabah al-Ahmad al-Jaber al-Sabah, emir of Kuwait, 83.

—Ruth Bader Ginsburg, U.S. Supreme Court associate justice, 79.

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Associated Press writers Paul Haven in Havana, Cuba; David Rising in Berlin; Seth Borenstein, Mark Sherman and Matt Yancey in Washington, and researcher Judy Ausuebel in New York contributed to this report.

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Marilynn Marchione can be followed at http://twitter.com/MMarchioneAP

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Boy with rifle, guns threatened to kill 23 classmates, police say

A 12-year-old student in northern San Diego County has been admitted to a hospital for "evaluation and treatment" after being taken into custody on suspicion of sending an email threatening to kill a teacher and 23 students, the Sheriff's Department said.

Detectives served a search warrant Saturday night at the student's home and seized several computers and "numerous" rifles and handguns, the Sheriff's Department said. The student was taken into custody as the warrant was being served.

The student is suspected of sending a threatening email Friday night to an administrator at Twin Peaks Middle School in Poway, mentioning 3,000 rounds of ammunition and threatening to shoot to kill a teacher and 23 students.

"There is no evidence to suggest anyone else was involved in making the threats and it is believed to be an isolated incident," according to Sgt. Dave Ross.

A task force of detectives and computer specialists from local, state and federal law enforcement agencies had tracked the email to the student's home, the Sheriff's Department said.

The case will be turned over to the San Diego County district attorney's office for evaluation.

ALSO:

Dorner manhunt: Search resumes in Big Bear mountains

Dorner manhunt: Officers opened fire on mother, daughter

Dorner had history of complaints against fellow LAPD officers

--Tony Perry in San Diego

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Syrian War Closes In on the Heart of Damascus

DAMASCUS, Syria — Unkempt government soldiers, some appearing drunk, have deployed near a rebel-held railway station in the southern reaches of this tense capital. Office workers on 29th of May Street, in the heart of the city, tell of huddling at their desks, trapped inside for hours by gun battles that sound alarmingly close.

Soldiers have swept through city neighborhoods, making arrests ahead of a threatened rebel advance downtown, even as opposition fighters edge past the city limits, carrying mortars and shelling security buildings. Fighter jets that pounded the suburbs for months have begun to strike Jobar, an outlying neighborhood of Damascus proper, creating the disturbing spectacle of a government’s bombing its own capital.

On Sunday, the government sent tanks there to battle rebels for control of a key ring road.

In this war of murky battlefield reports, it is hard to know whether the rebels’ recent forays past some of the capital’s circle of defenses — in an operation that they have, perhaps immodestly, named the “Battle of Armageddon” — will lead to more lasting gains than earlier offensives did. But travels along the city’s battlefronts in recent days made clear that new lines, psychological as much as geographical, had been crossed.

“I didn’t see my family for more than a year,” a government soldier from a distant province said in a rare outpouring of candor. He was checking drivers’ identifications near the railway station at a checkpoint where hundreds of soldiers arrived last week with tanks and other armored vehicles.

“I am tired and haven’t slept well for a week,” he said, confiding in a traveler who happened to be from his hometown. “I have one wish — to see my family and have a long, long sleep. Then I don’t care if I die.”

For months, this ancient city has hunched in a defensive crouch as fighting raged in suburbs that curve around the city’s south and east. On the western edge of the city, the palace of the embattled president, Bashar al-Assad, sits on a steep, well-defended ridge.

In between, Damascus, with its walled Old City, grand diagonal avenues and crowded working-class districts, has remained the eye of the storm. People keep going to work, even as electric service becomes sporadic and groceries dwindle, even as the road to the airport is often cut off by fighting outside the city, and even as smoke from artillery and airstrikes in nearby suburbs becomes a regular feature on the horizon.

But after rebels took the railway station 10 days ago in a city district called Qadam and attacked Abassiyeen Square on an approach to the city center on Wednesday, a new level of alarm and disorder has suffused the city. Rebels have pushed farther into the capital than at any point since July, when they briefly held part of a southern neighborhood.

Near the Qadam railway station last week, many of the government soldiers, their hair and beards untrimmed, wore disheveled or dirty uniforms and smelled as if they had not had showers in a long time. Some soldiers and security officers even appeared drunk, walking unsteadily with their weapons askew — a shocking sight in Syria, where regimented security forces and smartly uniformed officers have long been presented as a symbol of national pride.

The deployment appeared aimed at stopping the rebels from advancing past Qadam, either across the city’s ring road and toward the downtown or to suburbs to the east to close a gap in the opposition’s front line.

But even stationed here in Damascus, the heart of the government’s power, the soldier at the checkpoint — who was steady on his feet — said he felt vulnerable.

“It is very scary to spend a night and you expect to be shot or slaughtered at any moment,” he said. “We spend our nights counting the minutes until daytime.”

The government has hit back hard, striking Qadam with artillery and airstrikes, and making pre-emptive arrests in Midan, the neighboring district, closer to downtown, where rebels gained a temporary foothold in July and which they said was their next target in this latest offensive. Soldiers summarily executed four people in Qadam on Friday, according to the Local Coordinating Committees, an anti-Assad activist network, though it was unclear if the victims were would-be military defectors or captured rebels.

On a recent journey along the front line, a traveler saw soldiers speaking harshly to residents at checkpoints outside Yarmouk Camp, a long-contested area east of Qadam that is home to both Syrians and Palestinian refugees, who have lived there for decades. Rebels took over much of the camp in December, drawing government airstrikes that drove out most residents. But about 20 percent of those people appear to have returned, in part, they said, because the government had attacked another refugee camp where they had taken shelter.

A Palestinian refugee who gave only a nickname, Abu Muhammad, was carrying a sack of bread into the camp. He said that he had started out with three sacks for his wife and three sons, but that officers — he said they were from Mr. Assad’s Alawite sect — had shouted at him and confiscated two sacks, accusing him of taking bread to the rebels.

The government is pressuring Palestinians to take the camp back from the rebels, Abu Muhammad said. He said that was an absurd demand from a government that bombed its own people but made no response to last month’s airstrike by Israel. “Why doesn’t the regime send its ‘hero’ army to liberate the camp?” he said.

Another center of recent fighting is just northeast of the city. Rebels who have taken over much of the suburb of Qaboun recently pushed across the ring road there into the city neighborhood of Jobar. From there, said Abu Omar al-Jobrani, a leader of fighters in the area, they moved mortars close enough to attack a munitions factory and air force security headquarters near Abassiyeen Square, a roundabout that is near a major stadium and that provides access to downtown.

Reports of rebel strikes on Wednesday on such a central landmark, which appeared to be backed up by videos showing black smoke pouring across the plaza, raised new fears in the capital. The government closed the roads around the square, causing traffic jams deep into downtown, and sent dozens of security men to protect the Parliament building. Terrified residents of the centrally located Old City closed their shops.

Fighting continued over the weekend, as the government and rebels fought for control of the ring road near Jobar. Shells and airstrikes kept raining on the neighborhood, sending dust and smoke into the air, higher than the minarets on its mosques.

Anne Barnard reported from Beirut, Lebanon.

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